In the first section of this analysis and discussion activity, students learn that different versions of a gene give the instructions for making different versions of a clotting protein, which result in normal blood clotting or hemophilia.
Next, students learn how genes provide the instructions for making a protein via the processes of transcription and translation. They develop an understanding of the roles of RNA polymerase, the base-pairing rules, mRNA, tRNA and ribosomes.
Finally, students use their learning about transcription and translation to understand how a change in a single nucleotide in the hemoglobin gene can result in sickle cell anemia.
Throughout this activity, students use the information in brief explanations, figures and videos to answer analysis and discussion questions.
This activity can be used to introduce students to transcription and translation or to reinforce and enhance student understanding.
If you prefer a hands-on activity that uses simple paper models to simulate the molecular processes of transcription and translation, see “How Genes Can Cause Disease – Introduction to Transcription and Translation” (http://serendipstudio.org/sci_edu/waldron/#trans).
The Student Handout is available in the first two attached files and as a Google doc designed for use in online instruction and distance learning. (For additional instructions, see https://serendipstudio.org/exchange/bioactivities/Googledocs, especially item 7.) The Teacher Notes, available in the last two attached files, provide instructional suggestions and background information and explain how this activity is aligned with the Next Generation Science Standards (NGSS).
| Attachment | Size |
|---|---|
| TranscriptionTranslationSHO.docx | 4.4 MB |
| TranscriptionTranslationSHO.pdf | 955.88 KB |
| TranscriptionTranslationTN.docx | 3.1 MB |
| TranscriptionTranslationTN.pdf | 840.75 KB |
In the Student Handout, we have clarified some of the questions, explanations and figures. We have also added an analysis of sickle cell trait to introduce students to the molecular biology of a heterozygous individual.
Ingrid
Can you send me a copy of the answer key please? Thank you!
Please see the Teacher Notes for directions about how to request the key and other helpful information.
Can you sent me this answers key?
Please see the Teacher Notes for information about how to obtain the key, as well as background biology and instructional suggestions.
Hi I've helping some of my classmates about this topic can I have the the answer keys send to my email for reference. Thank you
Please see my response to the comment immediately below.
Thank you,
Ingrid
Hi, I am using this for my students. Could you send me an answer key?
Thank you for your message. Please see the Teacher Notes for information about how to obtain the key, as well as background biology and instructional suggestions.
The Student Handout has been streamlined and reorganized to facilitate student learning. The Student Handout now includes a final section with questions about how the coronavirus uses the cell’s ribosomes and molecules to make new viral proteins. The Teacher Notes include a brief introduction to replication of the coronavirus.
I want to have my Honors Biology class go this worksheet. Could you please send me an answer key?
Thank you for your message. Please see the Teacher Preparation Notes for information about how to get the key, as well as instructional suggestions and background biology.
Ingrid
The revised activity starts with much more well-developed anchor phenomena (hemophilia and sickle cell anemia). Subsequent sections are oriented to answer the guiding question “How can genes cause health problems?” In addition, this revision has clarified multiple explanations and questions and reorganized some of the material to facilitate student learning and understanding.
Looking for the answer key for : From Gene to Protein via transcription and translation.
Thanks so much
Lori
Griswold High School
Thank you for your message. Please see the Teacher Preparation Notes for information about how to get the key, as well as instructional suggestions and background biology.
Ingrid
I am looking to receive the answer key to this document. I have emailed twice to the email it provided but have received no answer. I really need this answer ASAP. Please help! Thank you so much!
I am sorry for your frustration. I usually respond to all key requests that I receive from school email addresses within a day or two, and I am currently up to date. I often ignore email requests from non-school email addresses, particularly if they are excessively brief, in the style of younger generations. Please send your request again from your school email address.
To improve student understanding of basic concepts, we have revised some of the explanations and questions in the Student Handout, added several figures, and improved other figures.
can you please send me the answer key for my students
Please see reply to message immediately below.
I am teacher at Oak Ridge High School, in Oak Ridge, Tn. I teach Biology to Special Education students that require the course to be divided into two years. I came across this site and liked the presentation of the material. I would appreciate a copy of the answer key.
Thank you for your appreciation. With regard to the key, please see the response below.
Hello,
I intend to use the student doc. as an opener and a review activity. Is it possible to receive the answer document?
Thank you for creating the "From Genes to Proteins" hands on,mind on activity.
Thank you for your message. Please see the Teacher Preparation Notes for information about how to get the key, as well as instructional suggestions and background biology.
I am a sub Bio teacher and I could really use some help grading this so I would love the answer key
Hi Ingrid, I would love to try out some of your genetics learning sequences with my senior biology classes - May I have access to the KEY?
Kind regards, Gill
Thank you for your message. Please see the Teacher Preparation Notes for information about how to get the key, as well as instructional suggestions and background biology.
This revision includes improved explanations, questions and figures. These changes are designed to improve student understanding and retention of important concepts. I'm grateful for helpful comments and suggestions from Dusty Carroll, Carrie Chait and other teachers.
The Student Handout includes more emphasis on having students actively construct their understanding of key points, with less explicit explanation. The Teacher Preparation Notes have improved the instructional suggestions and include a one-page quiz that can be used for summative assessment and/or to reinforce student learning.
Can i please have the asnwer key i have a test and i need to study and i need it as fast as possible !!
is there an answer key?
